Betahistine exerts a dose-dependent effect on cochlear stria vascularis blood flow in guinea pigs in vivo.

<h4>Objective</h4>Betahistine is a histamine H(1)-receptor agonist and H(3)-receptor antagonist that is administered to treat Menière's disease. Despite widespread use, its pharmacological mode of action has not been entirely elucidated. This study investigated the effect of betahis...

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Bibliographic Details
Main Authors: Fritz Ihler, Mattis Bertlich, Kariem Sharaf, Sebastian Strieth, Michael Strupp, Martin Canis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22745706/pdf/?tool=EBI