Dual-responsive supramolecular photodynamic nanomedicine with activatable immunomodulation for enhanced antitumor therapy

A major challenge facing photodynamic therapy (PDT) is that the activity of the immune-induced infiltrating CD8+ T cells is subject to the regulatory T lymphocytes (Tregs), leaving the tumor at risk of recurrence and metastasis after the initial ablation. To augment the antitumor response and reprog...

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Bibliographic Details
Main Authors: Siqin He, Lulu Wang, Dongxu Wu, Fan Tong, Huan Zhao, Hanmei Li, Tao Gong, Huile Gao, Yang Zhou
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523004008