PKM2 promotes lymphatic metastasis of hypopharyngeal carcinoma via regulating epithelial-mesenchymal transition: an experimental research

PKM2 promotes lymphatic metastasis of hypopharyngeal carcinoma via regulating epithelial-mesenchymal transition: an experimental research

Abstract Background Patients with hypopharyngeal carcinoma (HPC) have a poor prognosis mainly because of lymphatic metastasis. This research aimed to determine the PKM2 role in lymphatic metastasis in HPC and the underlying molecular mechanism contributing to this phenomenon. Methods PKM2 in HPC was...

Full description

Bibliographic Details
Main Authors: Xin Zhou, Yanshi Li, Min Pan, Tao Lu, Chuan Liu, Zhihai Wang, Fengxiang Tang, Guohua Hu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Diagnostic Pathology
Subjects:
Hypopharyngeal carcinoma
Lymphatic metastasis
Pyruvate kinase M2
Epithelial-mesenchymal transition
Foot-pad xenograft model
Online Access:https://doi.org/10.1186/s13000-024-01474-5

Internet

https://doi.org/10.1186/s13000-024-01474-5

Similar Items