Selective Estrogen Receptor Modulator-Like Activities of Herba epimedii Extract and its Interactions With Tamoxifen and Raloxifene in Bone Cells and Tissues

Selective Estrogen Receptor Modulator-Like Activities of Herba epimedii Extract and its Interactions With Tamoxifen and Raloxifene in Bone Cells and Tissues

Herbaepimedii (HEP), a kidney-tonifying herb, has been commonly used alone or in formula for strengthening kidney function and treating bone disorders. Its bone protective activity has been demonstrated to be via estrogen receptor (ERs). HEP activates the phosphorylation of ERα in an estrogen respon...

Full description

Bibliographic Details
Main Authors: Liping Zhou, Ka-Ying Wong, Wenxuan Yu, Christina Chui-Wa Poon, Huihui Xiao, Chi-On Chan, Daniel Kam-Wah Mok, Yan Zhang, Man-Sau Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
Herba epimedii
SERMs
postmenopausal osteoporosis
herb-drug interactions
estrogen receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.571598/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.571598/full

Similar Items