Lipid bilayer-atomic force microscopy combined platform records simultaneous electrical and topological changes of the TRP channel polycystin-2 (TRPP2).

Ion channels are transmembrane proteins that mediate ion transport across biological membranes. Ion channel function is traditionally characterized by electrical parameters acquired with techniques such as patch-clamping and reconstitution in lipid bilayer membranes (BLM) that provide relevant infor...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Sumit Lal, Noelia Scarinci, Paula L Perez, María Del Rocío Cantero, Horacio F Cantiello
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science (PLoS) 2018-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC6104948?pdf=render