Determination of Some Isoquinoline Alkaloids in Extracts Obtained from Selected Plants of the Ranunculaceae, Papaveraceae and Fumarioideae Families by Liquid Chromatography and In Vitro and In Vivo Investigations of Their Cytotoxic Activity

Determination of Some Isoquinoline Alkaloids in Extracts Obtained from Selected Plants of the Ranunculaceae, Papaveraceae and Fumarioideae Families by Liquid Chromatography and In Vitro and In Vivo Investigations of Their Cytotoxic Activity

Alkaloids are heterocyclic bases with widespread occurrence in nature. Plants are rich and easily accessible sources of them. Most isoquinoline alkaloids have cytotoxic activity for different types of cancer, including malignant melanoma, the most aggressive type of skin cancer. The morbidity of mel...

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Bibliographic Details
Main Authors: Justyna Misiurek, Tomasz Plech, Barbara Kaproń, Anna Makuch-Kocka, Małgorzata Szultka-Młyńska, Bogusław Buszewski, Anna Petruczynik
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
cytotoxic activity
danio rerio larvae xenograft model
HPLC-DAD
LC-MS/MS
isoquinoline alkaloids
plant extracts
Online Access:https://www.mdpi.com/1420-3049/28/8/3503

Internet

https://www.mdpi.com/1420-3049/28/8/3503

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