The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease

The proto-oncogene SKI is highly expressed in human myeloid leukemia and also in murine hematopoietic stem cells. However, its operative relevance in these cells remains elusive. We have over-expressed SKI to define its intrinsic role in hematopoiesis and myeloid neoplasms, which resulted in a robus...

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Bibliographic Details
Main Authors: Sofie Singbrant, Meaghan Wall, Jennifer Moody, Göran Karlsson, Alistair M. Chalk, Brian Liddicoat, Megan R. Russell, Carl R. Walkley, Stefan Karlsson
Format: Article
Language:English
Published: Ferrata Storti Foundation 2014-04-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/6994