The pomegranate-derived peptide Pug-4 alleviates nontypeable Haemophilus influenzae-induced inflammation by suppressing NF-kB signaling and NLRP3 inflammasome activation

The pomegranate-derived peptide Pug-4 alleviates nontypeable Haemophilus influenzae-induced inflammation by suppressing NF-kB signaling and NLRP3 inflammasome activation

The respiratory pathogen nontypeable Haemophilus influenzae (NTHi) is the most common cause of exacerbation of chronic obstructive pulmonary disease (COPD), of which an excessive inflammatory response is a hallmark. With the limited success of current medicines there is an urgent need for the develo...

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Bibliographic Details
Main Authors: Pornpimon Jantaruk, Sittiruk Roytrakul, Anchalee Sistayanarain, Duangkamol Kunthalert
Format: Article
Language:English
Published: PeerJ Inc. 2024-02-01
Series:PeerJ
Subjects:
Nontypaeble Haemophilus influenzae
NTHi
COPD
Interleukin-1β
IL-1β
NF-κB
Online Access:https://peerj.com/articles/16938.pdf

Internet

https://peerj.com/articles/16938.pdf

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