A multiplex CRISPR interference tool for virulence gene interrogation in Legionella pneumophila
Ellis et al. present a multiplex CRISPR interference tool for Legionella pneumophila, the intracellular pathogen responsible for Legionnaires’ disease. This valuable new tool enables precise interrogation of multiple virulence genes simultaneously during host infection.
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-02-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-01672-7 |