The Central Conserved Region (CCR) of Respiratory Syncytial Virus (RSV) G Protein Modulates Host miRNA Expression and Alters the Cellular Response to Infection

The Central Conserved Region (CCR) of Respiratory Syncytial Virus (RSV) G Protein Modulates Host miRNA Expression and Alters the Cellular Response to Infection

Respiratory Syncytial Virus (RSV) infects respiratory epithelial cells and deregulates host gene expression by many mechanisms including expression of RSV G protein (RSV G). RSV G protein encodes a central conserved region (CCR) containing a CX3C motif that functions as a fractalkine mimic. Disrupti...

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Bibliographic Details
Main Authors: Abhijeet A. Bakre, Jennifer L. Harcourt, Lia M. Haynes, Larry J. Anderson, Ralph A. Tripp
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Vaccines
Subjects:
respiratory syncytial virus
RSV
microRNAs
CX3CR1
IFNλ
Online Access:https://www.mdpi.com/2076-393X/5/3/16

Internet

https://www.mdpi.com/2076-393X/5/3/16

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