Fingolimod (FTY720) stimulates Ca(2+)/calcineurin signaling in fission yeast.
Fingolimod hydrochloride (FTY720) is the first in class of sphingosine 1-phosphate (S1P) receptor modulator approved to treat multiple sclerosis via down-regulation of G protein-coupled S1P receptor 1 by its phosphorylated form (FTY720-P). Many studies have revealed that FTY720 exerts various biolog...
Những tác giả chính: | , , , , , , , , , |
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Định dạng: | Bài viết |
Ngôn ngữ: | English |
Được phát hành: |
Public Library of Science (PLoS)
2013-01-01
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Loạt: | PLoS ONE |
Truy cập trực tuyến: | http://europepmc.org/articles/PMC3849299?pdf=render |