AXL Inhibition Extinguishes Primitive JAK2 Mutated Myeloproliferative Neoplasm Progenitor Cells

Abstract. Myeloproliferative neoplasms (MPN) are clonal stem cell associated disorders inclusive of chronic myeloid leukemia (CML), Polycythaemia vera (PV), myelofibrosis (MF), and essential thrombocythemia (ET). They are characterized by increased production of myeloid cells with minimal effects on...

Full description

Bibliographic Details
Main Authors: Stella Pearson, Rognvald Blance, Tim C.P. Somervaille, Anthony D. Whetton, Andrew Pierce
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000233