Physiological cell bioprinting density in human bone-derived cell-laden scaffolds enhances matrix mineralization rate and stiffness under dynamic loading

Physiological cell bioprinting density in human bone-derived cell-laden scaffolds enhances matrix mineralization rate and stiffness under dynamic loading

Human organotypic bone models are an emerging technology that replicate bone physiology and mechanobiology for comprehensive in vitro experimentation over prolonged periods of time. Recently, we introduced a mineralized bone model based on 3D bioprinted cell-laden alginate-gelatin-graphene oxide hyd...

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Bibliographic Details
Main Authors: Anke M. de Leeuw, Reto Graf, Pei Jin Lim, Jianhua Zhang, Gian Nutal Schädli, Sheila Peterhans, Marianne Rohrbach, Cecilia Giunta, Matthias Rüger, Marina Rubert, Ralph Müller
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
cell-laden scaffold
cell density
3D bioprinting
dynamic culture
time-lapsed micro-CT
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1310289/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2024.1310289/full

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