Development of a ferroptosis-based model to predict prognosis, tumor microenvironment, and drug response for lung adenocarcinoma with weighted genes co-expression network analysis

Development of a ferroptosis-based model to predict prognosis, tumor microenvironment, and drug response for lung adenocarcinoma with weighted genes co-expression network analysis

Objective: The goal of this study was to create a risk model based on the ferroptosis gene set that affects lung adenocarcinoma (LUAD) patients’ prognosis and to investigate the potential underlying mechanisms.Material and Methods: A cohort of 482 LUAD patients from the TCGA database was used to dev...

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Bibliographic Details
Main Authors: Tao Cheng, Guangyao Shan, Huiqin Yang, Jie Gu, Chunlai Lu, Fengkai Xu, Di Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
ferroptosis
WGCNA
lung adenocarcinoma
bioinformatics analysis
prognosis
immune microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1072589/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1072589/full

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