Bioengineered silkworm model for expressing human neurotrophin-4 with potential biomedical application

Neurotrophin-4 (NT-4) is a neurotrophic factor that plays important roles in maintaining nerve cell survival, regulating neuronal differentiation and apoptosis, and promoting nerve injury repair. However, the source of sufficient NT-4 protein and efficient delivery of NT-4 remain a challenge. This s...

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Bibliographic Details
Main Authors: Wenchang Zhang, Zhiqing Li, Weiqun Lan, Hao Guo, Feng Chen, Feng Wang, Guanwang Shen, Qingyou Xia, Ping Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.1104929/full