Poly (ADP-ribose) polymerases as PET imaging targets for central nervous system diseases

Poly (ADP-ribose) polymerases (PARPs) constitute of 17 members that are associated with divergent cellular processes and play a crucial role in DNA repair, chromatin organization, genome integrity, apoptosis, and inflammation. Multiple lines of evidence have shown that activated PARP1 is associated...

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Bibliographic Details
Main Authors: Jie Tong, Baosheng Chen, Peng Wen Tan, Stephen Kurpiewski, Zhengxin Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1062432/full