Theoretical Assessment of the Ligand/Metal/Quadruplex Recognition in the Non-Canonical Nucleic Acids Structures
Quadruplexes (GQs), peculiar DNA/RNA motifs concentrated in specific genomic regions, play a vital role in biological processes including telomere stability and, hence, represent promising targets for anticancer therapy. GQs are formed by folding guanine-rich sequences into square planar G-tetrads w...
Автори: | , , , , , |
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Формат: | Стаття |
Мова: | English |
Опубліковано: |
MDPI AG
2023-08-01
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Серія: | Molecules |
Предмети: | |
Онлайн доступ: | https://www.mdpi.com/1420-3049/28/16/6109 |