Germinal centers are permissive to subdominant antibody responses

Germinal centers are permissive to subdominant antibody responses

IntroductionA protective humoral response to pathogens requires the development of high affinity antibodies in germinal centers (GC). The combination of antigens available during immunization has a strong impact on the strength and breadth of the antibody response. Antigens can display various level...

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Bibliographic Details
Main Authors: Philippe A. Robert, Theinmozhi Arulraj, Michael Meyer-Hermann
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
germinal center (GC)
agent-based model (ABM)
vaccine model
immunodominance (ID)
antibodies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1238046/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1238046/full

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