β-adrenergic signaling triggers enteric glial reactivity and acute enteric gliosis during surgery

β-adrenergic signaling triggers enteric glial reactivity and acute enteric gliosis during surgery

Abstract Background Enteric glia contribute to the pathophysiology of various intestinal immune-driven diseases, such as postoperative ileus (POI), a motility disorder and common complication after abdominal surgery. Enteric gliosis of the intestinal muscularis externa (ME) has been identified as pa...

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Bibliographic Details
Main Authors: Patrick Leven, Reiner Schneider, Linda Schneider, Shilpashree Mallesh, Pieter Vanden Berghe, Philipp Sasse, Jörg C. Kalff, Sven Wehner
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Neuroinflammation
Subjects:
Enteric glia
RiboTag
Gut inflammation
Postoperative ileus
Sympathetic nervous system
Neuroimmunology
Online Access:https://doi.org/10.1186/s12974-023-02937-0

Internet

https://doi.org/10.1186/s12974-023-02937-0

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