β-adrenergic signaling triggers enteric glial reactivity and acute enteric gliosis during surgery

β-adrenergic signaling triggers enteric glial reactivity and acute enteric gliosis during surgery

Abstract Background Enteric glia contribute to the pathophysiology of various intestinal immune-driven diseases, such as postoperative ileus (POI), a motility disorder and common complication after abdominal surgery. Enteric gliosis of the intestinal muscularis externa (ME) has been identified as pa...

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Detalles Bibliográficos
Autores principales: Patrick Leven, Reiner Schneider, Linda Schneider, Shilpashree Mallesh, Pieter Vanden Berghe, Philipp Sasse, Jörg C. Kalff, Sven Wehner
Formato: Artículo
Lenguaje:English
Publicado: BMC 2023-11-01
Colección:Journal of Neuroinflammation
Materias:
Enteric glia
RiboTag
Gut inflammation
Postoperative ileus
Sympathetic nervous system
Neuroimmunology
Acceso en línea:https://doi.org/10.1186/s12974-023-02937-0

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