Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

Osteosarcoma (OS) is a kind of malignant tumor originating from mesenchymal tissue Bone mesenchymal stem cells-derived extracellular vesicles (BMSCs-EVs) can play important roles in OS. This study investigated the mechanism of BMSCs-EVs on OS. BMSC surface antigens and adipogenic and osteogenic dif...

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Bibliographic Details
Main Authors: Alimu Keremu, Pazila Aila, Aikebaier Tusun, Maimaitiaili Abulikemu, Xiaoguang Zou
Format: Article
Language:English
Published: PAGEPress Publications 2022-06-01
Series:European Journal of Histochemistry
Subjects:
Osteosarcoma
bone mesenchymal stem cells
extracellular vesicle
miR-206
NRSN2
ERK1/2-Bcl-xL
Online Access:https://www.ejh.it/index.php/ejh/article/view/3394

Internet

https://www.ejh.it/index.php/ejh/article/view/3394

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