miRNA displacement as a promising approach for cancer therapy

microRNA (miRNA) are critical post-transcriptional regulators and key players in diseases development. We demonstrated that non-canonical microRNA Responsive Elements (here MRE-16) could sequester miR-16, dampening miR-16 tumor suppressor function. We developed small oligonucleotides, masking specif...

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Bibliographic Details
Main Authors: David Gilot, Marie-Dominique Galibert
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2017.1406432