Tramadol and Tapentadol Induce Conditioned Place Preference with a Differential Impact on Rewarding Memory and Incubation of Craving

Tramadol and Tapentadol Induce Conditioned Place Preference with a Differential Impact on Rewarding Memory and Incubation of Craving

Tramadol and tapentadol, synthetic opioids commonly prescribed for moderate-to-severe pain, have a unique pharmacology that optimizes their analgesia and safety. However, they are not devoid of risks, presenting addictive, abuse, and dependence potential. While tramadol-reinforcing properties have b...

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Bibliographic Details
Main Authors: Joana Barbosa, Sandra Leal, Frederico C. Pereira, Ricardo Jorge Dinis-Oliveira, Juliana Faria
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceuticals
Subjects:
tramadol
tapentadol
conditioned place preference
rewarding memory
incubation of craving
abuse
Online Access:https://www.mdpi.com/1424-8247/16/1/86

Internet

https://www.mdpi.com/1424-8247/16/1/86

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