Human intestinal epithelial cells can internalize luminal fungi via LC3-associated phagocytosis

Human intestinal epithelial cells can internalize luminal fungi via LC3-associated phagocytosis

BackgroundIntestinal epithelial cells (IECs) are the first to encounter luminal microorganisms and actively participate in intestinal immunity. We reported that IECs express the β-glucan receptor Dectin-1, and respond to commensal fungi and β-glucans. In phagocytes, Dectin-1 mediates LC3-associated...

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Bibliographic Details
Main Authors: Sarit Cohen-Kedar, Efrat Shaham Barda, Keren Masha Rabinowitz, Danielle Keizer, Hanan Abu-Taha, Shoshana Schwartz, Kawsar Kaboub, Liran Baram, Eran Sadot, Ian White, Nir Wasserberg, Meirav Wolff-Bar, Adva Levy-Barda, Iris Dotan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
Candida albicans
intestinal epithelial cells
LC3-associated phagocytosis
organoids
dectin-1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1142492/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1142492/full

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