Intrinsic features of Zika Virus non-structural proteins NS2A and NS4A in the regulation of viral replication.

Zika virus (ZIKV) is a mosquito-borne flavivirus and can cause neurodevelopmental disorders in fetus. As a neurotropic virus, ZIKV persistently infects neural tissues during pregnancy but the viral pathogenesis remains largely unknown. ZIKV has a positive-sense and single-stranded RNA genome, which...

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Bibliographic Details
Main Authors: Yufeng Yu, Chengfeng Gao, Chunxia Wen, Peng Zou, Xian Qi, Carol J Cardona, Zheng Xing
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0010366