Cardiac Rhythm and Molecular Docking Studies of Ion Channel Ligands with Cardiotoxicity in Zebrafish

Cardiac Rhythm and Molecular Docking Studies of Ion Channel Ligands with Cardiotoxicity in Zebrafish

Safety is one of the most important and critical issues in drug development. Many drugs were abandoned in clinical trials and retracted from the market because of unknown side effects. Cardiotoxicity is one of the most common reasons for drug retraction due to its potential side effects, i.e., induc...

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Bibliographic Details
Main Authors: Bonifasius Putera Sampurna, Fiorency Santoso, Jia-Hau Lee, Wen-Hao Yu, Chin-Chung Wu, Gilbert Audira, Stevhen Juniardi, Jung-Ren Chen, Ying-Ting Lin, Chung-Der Hsiao
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cells
Subjects:
zebrafish
heart
ion channel ligand
cardiotoxicity
molecular docking
Online Access:https://www.mdpi.com/2073-4409/8/6/566

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https://www.mdpi.com/2073-4409/8/6/566

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