Role of the cGAS/STING pathway in the control of Brucella abortus infection acquired through the respiratory route

Role of the cGAS/STING pathway in the control of Brucella abortus infection acquired through the respiratory route

Despite the importance of the respiratory route for Brucella transmission, the lung immune response to this pathogen is scarcely characterized. We investigated the role of the cGAS/STING pathway of microbial DNA recognition in the control of respiratory Brucella infection. After in vitro B. abortus...

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Bibliographic Details
Main Authors: Iván M. Alonso Paiva, Raiany A. Santos, Camila B. Brito, Mariana C. Ferrero, Juan Manuel Ortiz Wilczyñski, Eugenio A. Carrera Silva, Sergio C. Oliveira, Pablo C. Baldi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
Brucella
respiratory infection
STING
cGAS
proinflammatory cytokines
innate immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1116811/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1116811/full

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