Impact of the new membrane-targeting lipoglycopeptide antibiotic MCC5145 on the treatment of bacteremic pneumococcal pneumonia in mice

Impact of the new membrane-targeting lipoglycopeptide antibiotic MCC5145 on the treatment of bacteremic pneumococcal pneumonia in mice

ABSTRACT Bacteremic Streptococcus pneumoniae pneumonia is one of the most severe forms of invasive pneumococcal disease (IPD) and with particularly high case-fatality rates among the elderly and individuals with comorbidities, exacerbated by rising antibiotic resistance and time to initiation of the...

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Bibliographic Details
Main Authors: Abiodun D. Ogunniyi, Hang Thi Nguyen, Karl A. Hansford, Matthew A. Cooper, Darren J. Trott, Mark A. T. Blaskovich
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
Streptococcus pneumoniae
pneumococcus
pneumonia
immunocompromised hosts
lipoglycopeptide
bioluminescence
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04459-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.04459-22

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