Synergistic influence of cytokine gene polymorphisms over the risk of dementia: A multifactor dimensionality reduction analysis

Synergistic influence of cytokine gene polymorphisms over the risk of dementia: A multifactor dimensionality reduction analysis

ObjectiveEvidence supports the important role of neuroinflammation in some types of dementia. This study aimed to evaluate the effect of epistasis of gene cytokines such as interleukin (IL)-α, IL-6, tumor necrosis factor (TNFα), and interferon-gamma (IFN-γ) on the susceptibility to the development o...

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Bibliographic Details
Main Authors: Teresa Juárez-Cedillo, Nancy Martínez-Rodríguez, Gilberto Vargas-Alarcon, Enrique Juárez-Cedillo, Antonio Valle-Medina, Osvaldo Garrido-Acosta, Alfredo Ramirez
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
polymorphism
cytokine genes
dementia
MDR
gene–gene interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.952173/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2022.952173/full

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