I<sub>Ks</sub> Activator ML277 Mildly Affects Repolarization and Arrhythmic Outcome in the CAVB Dog Model

Long QT syndrome type 1 with affected I<sub>Ks</sub> is associated with a high risk for developing Torsade de Pointes (TdP) arrhythmias and eventually sudden cardiac death. Therefore, it is of high interest to explore drugs that target I<sub>Ks</sub> as antiarrhythmics. We ex...

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Bibliographic Details
Main Authors: Joanne J. A. van Bavel, Henriëtte D. M. Beekman, Agnieszka Smoczyńska, Marcel A. G. van der Heyden, Marc A. Vos
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/4/1147