Induction of AHR Gene Expression in Colorectal Cancer Cell Lines by Cucurbitacin D, E, and I

Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor and its induction may result in suppressing of cell proliferation in colorectal cancer (CRC). Cucurbitacin D (CucD), E (CucE) and I (CucI) are plant derived metabolites that inhibit cancer cells. This study aimed to evaluate...

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Bibliographic Details
Main Authors: Younes Aftabi, Habib Zarredar, Mohammadreza Sheikhi, Zahra Khoshkam, Abasalt Hosseinzadeh Colagar
Format: Article
Language:English
Published: Ferdowsi University of Mashhad 2019-03-01
Series:Journal of Cell and Molecular Research
Subjects:
Online Access:https://jcmr.um.ac.ir/article_29516_e06ad1773f35704adab1b9e8d4865167.pdf