Noodles, the all-in-one system for on-target efficiency analysis of CRISPR guide RNAs

Noodles, the all-in-one system for on-target efficiency analysis of CRISPR guide RNAs

The efficiency of clustered regularly interspaced short palindromic repeats (CRISPR) guide RNA (gRNA) targeting is critical for CRISPR associated protein 9 (Cas9)-dependent genomic modifications. Here, we developed Noodles, an all-in-one system to test the on-target activity of gRNAs easily and effi...

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Bibliographic Details
Main Authors: Dongfa Lin, Syeda Sadia Najam, Yu Liu, Nicola Murgia, Ilya A. Vinnikov
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:MethodsX
Subjects:
Noodles: CRISPR on-target efficiency analyzer
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016123004776

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http://www.sciencedirect.com/science/article/pii/S2215016123004776

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