Phe-140 Determines the Catalytic Efficiency of Arylacetonitrilase from <i>Alcaligenes faecalis</i>

Phe-140 Determines the Catalytic Efficiency of Arylacetonitrilase from <i>Alcaligenes faecalis</i>

Arylacetonitrilase from <i>Alcaligenes faecalis</i> ATCC8750 (NitAF) hydrolyzes various arylacetonitriles to the corresponding carboxylic acids. A systematic strategy of amino acid residue screening through sequence alignment, followed by homology modeling and biochemical confirmation wa...

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Bibliographic Details
Main Authors: Jung-Soo Kim, Sanjay K. S. Patel, Manish K. Tiwari, Chunfen Lai, Anurag Kumar, Young Sin Kim, Vipin Chandra Kalia, Jung-Kul Lee
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Alcaligenes faecalis</i>
arylacetonitrilase
catalytic efficiency
Online Access:https://www.mdpi.com/1422-0067/21/21/7859

Internet

https://www.mdpi.com/1422-0067/21/21/7859

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