Insights about genome function from spatial organization of the genome

Insights about genome function from spatial organization of the genome

Abstract Over the last 15 years, development of chromosome conformation capture (3C) and its subsequent high-throughput variants in conjunction with the fast development of sequencing technology has allowed investigators to generate large volumes of data giving insights into the spatial three-dimens...

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Bibliographic Details
Main Authors: Shuvra Shekhar Roy, Ananda Kishore Mukherjee, Shantanu Chowdhury
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Human Genomics
Subjects:
Genome architecture
Chromosome conformation capture (3C)
Hi-C
Topologically associated domains (TAD)
Chromatin looping
Histone modifications
Online Access:http://link.springer.com/article/10.1186/s40246-018-0140-z

Internet

http://link.springer.com/article/10.1186/s40246-018-0140-z

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