Exploring immune response toward transplanted human kidney tissues assembled from organoid building blocks

Summary: The increasing scarcity of organs and the significant morbidity linked to dialysis require the development of engineered kidney tissues from human-induced pluripotent stem cells. Integrative approaches that synergize scalable kidney organoid differentiation, tissue biomanufacturing, and com...

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Bibliographic Details
Main Authors: Thiago J. Borges, Yoshikazu Ganchiku, Jeffrey O. Aceves, Ronald van Gaal, Sebastien G.M. Uzel, Ivy A. Rosales, Jonathan E. Rubins, Kenichi Kobayashi, Ken Hiratsuka, Murat Tekguc, Guilherme T. Ribas, Karina Lima, Rodrigo B. Gassen, Ryuji Morizane, Jennifer A. Lewis, Leonardo V. Riella
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224021825