Tailored anticoagulant treatment after a first venous thromboembolism: protocol of the Leiden Thrombosis Recurrence Risk Prevention (L-TRRiP) study - cohort-based randomised controlled trial

Introduction Patients with a first venous thromboembolism (VTE) are at risk of recurrence. Recurrent VTE (rVTE) can be prevented by extended anticoagulant therapy, but this comes at the cost of an increased risk of bleeding. It is still uncertain whether patients with an intermediate recurrence risk...

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Main Authors: Saskia le Cessie, Nick van Es, Michiel Coppens, Karina Meijer, Suzanne C Cannegieter, Saskia Middeldorp, Menno V Huisman, Frederikus A Klok, Geert-Jan Geersing, Annette W G van der Velden, Elske M van den Akker-van Marle, Albert T A Mairuhu, M Elske van den Akker-van Marle, Laura M Faber, Tjerk de Nijs, Remy H H Bemelmans, Coen van Guldener, Marcel A van de Ree, Marieke J.H. Wermer, Tessa Elling, Carolien van Netten, Milou A M Stals, Rick Roos, J Louise I Burggraaf-van Delft, Nienke van Rein, Jan-Willem K van den Berg, Coty Y Bruggeman, Marissa Cloos-van Balen, Matthijs Eefting, Yvonne Ende-Verhaar, Wouter K de Jong, Fleur Kleijwegt, Ted Koster, Cees Kroon, Saskia Kuipers, Jenneke Leentjens, Dieuwke Luijten, Ilse Schrover, Janneke Swart-Heikens, Yavuz Bilgin, Marleen Goddrie, Pieter Jobse, Suzanne Jong, Brianne Murphy, Carla Boekholt, Danick Werner, Laura Kratz, Marjolein Kremers, Monique Schilders, Gideon Hajer, Bas Langeveld, Saskia Teunisse-de Recht, Annemiek Bogerd, Ymke Broers, Stan Kolman, Sanjay Sankatsing, Lenneke van Tol, Edith Beishuizen, Shantie Bharatsingh, Edith Boersma, Annemarie van der Kraan-Donker, Sabine van Arnhem, Fransien Croon-de Boer, Ad Dees, J P (Hanneke) van Embden, Roxane Heller, Merel Hoogendorp, Roel Jonkhoff, Roel J J M van de Laar, Corry Leunis-de Ruiter, Patricia Scherpenisse-Klopstra, Tom L H Stellema, Kim Warink, Lizanne E van den Akker, Eleonora C Camilleri, Tess R C Huibregtse, Ingeborg de Jonge, Ruben Y Kok, Inger N Kunnekes, Lejla Mahic, Hinke C Nagtegaal, Petra J Noordijk, Hülya Oztürk, Alexia M van der Ploeg, Vibeke Schmidt, Anne-Marie Schuitemaker, Vera C Slootweg, Mark J R Smeets, Milou Thibaudier, Marco Dam, Swopkje de Jong, Hanneke van der Velde, Evertine Abbink, Carlinda Bresser, Simone Sissing, Soerajja Bhoelan, Èmese Heijkoop, Francien Huisman, Mark Lenssen, Anja B U Makelburg, Karen H Thedinga, Marja A J Voskuilen, Femke Yspeerd, Sandra Brookman, Titia Lamberts, Inge Paas, Janneke Swart Heikens, Janneke van den Brink, Aline van de Vendel, Ellis S. van Etten
Format: Article
Language:English
Published: BMJ Publishing Group 2024-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/14/3/e078676.full