Bifunctional molecules targeting SARS-CoV-2 spike and the polymeric Ig receptor display neutralization activity and mucosal enrichment

Bifunctional molecules targeting SARS-CoV-2 spike and the polymeric Ig receptor display neutralization activity and mucosal enrichment

The global health crisis and economic tolls of COVID-19 necessitate a panoply of strategies to treat SARS-CoV-2 infection. To date, few treatment options exist, although neutralizing antibodies against the spike glycoprotein have proven to be effective. Because infection is initiated at the mucosa a...

Full description

Bibliographic Details
Main Authors: Ian White, Ninkka Tamot, Rajitha Doddareddy, Jason Ho, Qun Jiao, Paul B. Harvilla, Tong-Yuan Yang, Brian Geist, M. Jack Borrok, Matthew D. Truppo, Rajkumar Ganesan, Partha Chowdhury, Adam Zwolak
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:mAbs
Subjects:
Polymeric Ig receptor
pIgR
sars-cov-2. coronavirus
antibody
Igg
bifunctional
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2021.1987180

Internet

https://www.tandfonline.com/doi/10.1080/19420862.2021.1987180

Similar Items