Rare-Earth Metal Complexes of the Antibacterial Drug Oxolinic Acid: Synthesis, Characterization, DNA/Protein Binding and Cytotoxicity Studies

Rare-Earth Metal Complexes of the Antibacterial Drug Oxolinic Acid: Synthesis, Characterization, DNA/Protein Binding and Cytotoxicity Studies

“Drug repositioning” is a current trend which proved useful in the search for new applications for existing, failed, no longer in use or abandoned drugs, particularly when addressing issues such as bacterial or cancer cells resistance to current therapeutic approaches. In this context, six new compl...

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Bibliographic Details
Main Authors: Ana-Madalina Maciuca, Alexandra-Cristina Munteanu, Mirela Mihaila, Mihaela Badea, Rodica Olar, George Mihai Nitulescu, Cristian V. A. Munteanu, Marinela Bostan, Valentina Uivarosi
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Molecules
Subjects:
drug repositioning
quinolone
oxolinic acid
rare-earth metal ions
anticancer
DNA binding
Online Access:https://www.mdpi.com/1420-3049/25/22/5418

Internet

https://www.mdpi.com/1420-3049/25/22/5418

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