Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial.

BACKGROUND:Previous research indicates that a combination vaccine targeting different stages of the malaria life cycle is likely to provide the most effective malaria vaccine. This trial was the first to combine two existing vaccination strategies to produce a vaccine that induces immune responses t...

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Bibliographic Details
Main Authors: Fiona M Thompson, David W Porter, Shinji L Okitsu, Nicole Westerfeld, Denise Vogel, Stephen Todryk, Ian Poulton, Simon Correa, Claire Hutchings, Tamara Berthoud, Susanna Dunachie, Laura Andrews, Jack L Williams, Robert Sinden, Sarah C Gilbert, Gerd Pluschke, Rinaldo Zurbriggen, Adrian V S Hill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2204057?pdf=render