The early activation of toll-like receptor (TLR)-3 initiates kidney injury after ischemia and reperfusion.

The early activation of toll-like receptor (TLR)-3 initiates kidney injury after ischemia and reperfusion.

Acute kidney injury (AKI) is one of the most important complications in hospitalized patients and its pathomechanisms are not completely elucidated. We hypothesize that signaling via toll-like receptor (TLR)-3, a receptor that is activated upon binding of double-stranded nucleotides, might play a cr...

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Bibliographic Details
Main Authors: Patrick Paulus, Katrin Rupprecht, Patrick Baer, Nicholas Obermüller, Daniela Penzkofer, Christin Reissig, Bertram Scheller, Johannes Holfeld, Kai Zacharowski, Stefanie Dimmeler, Joelle Schlammes, Anja Urbschat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3988056?pdf=render

Internet

http://europepmc.org/articles/PMC3988056?pdf=render

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