Oxidative Stress-Induced TRPV2 Expression Increase Is Involved in Diabetic Cataracts and Apoptosis of Lens Epithelial Cells in a High-Glucose Environment

Oxidative Stress-Induced TRPV2 Expression Increase Is Involved in Diabetic Cataracts and Apoptosis of Lens Epithelial Cells in a High-Glucose Environment

Cataracts are a serious complication of diabetes. In long-term hyperglycemia, intracellular Ca<sup>2+</sup> concentration ([Ca<sup>2+</sup>]<sub>i</sub>) and reactive oxygen species (ROS) are increased. The apoptosis of lens epithelial cells plays a key role in th...

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Bibliographic Details
Main Authors: Linghui Chen, Yanzhuo Chen, Wen Ding, Tao Zhan, Jie Zhu, Lesha Zhang, Han Wang, Bing Shen, Yong Wang
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
TRPV2
diabetic cataract
apoptosis
human lens epithelial cell
Online Access:https://www.mdpi.com/2073-4409/11/7/1196

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https://www.mdpi.com/2073-4409/11/7/1196

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