Macrophages-derived Factor XIII links coagulation to inflammation in COPD

Macrophages-derived Factor XIII links coagulation to inflammation in COPD

BackgroundThe local, extravascular, activation of the coagulation system in response to injury is a key factor mediating the resulting inflammatory response. Coagulation Factor XIIIA (FXIIIA) found in alveolar macrophages (AM) and dendritic cells (DC), by influencing fibrin stability, might be an in...

Full description

Bibliographic Details
Main Authors: Erica Bazzan, Alvise Casara, Claudia Maria Radu, Mariaenrica Tinè, Davide Biondini, Eleonora Faccioli, Federica Pezzuto, Nicol Bernardinello, Maria Conti, Elisabetta Balestro, Fiorella Calabrese, Paolo Simioni, Federico Rea, Graziella Turato, Paolo Spagnolo, Manuel G. Cosio, Marina Saetta
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
COPD - chronic obstructive pulmonary disease
macrophage
coagulation
inflammation
injury
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1131292/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1131292/full

Similar Items