EV products obtained from iPSC-derived MSCs show batch-to-batch variations in their ability to modulate allogeneic immune responses in vitro

EV products obtained from iPSC-derived MSCs show batch-to-batch variations in their ability to modulate allogeneic immune responses in vitro

Mesenchymal stromal cells (MSCs) have demonstrated therapeutic potential in diverse clinical settings, largely due to their ability to produce extracellular vesicles (EVs). These EVs play a pivotal role in modulating immune responses, transforming pro-inflammatory cues into regulatory signals that f...

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Bibliographic Details
Main Authors: Tobias Tertel, Robin Dittrich, Pierre Arsène, Arne Jensen, Bernd Giebel
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
exosomes
EV products
iPSC-derived MSCs
heterogeneity
immune modulation
quality control
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1282860/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1282860/full

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