Population Pharmacokinetics and Dosing Regimen of Lithium in Chinese Patients With Bipolar Disorder

Population Pharmacokinetics and Dosing Regimen of Lithium in Chinese Patients With Bipolar Disorder

Background: Lithium is an effective medication approved for the treatment of bipolar disorder (BD). It has a narrow therapeutic index (TI) and requires therapeutic drug monitoring. This study aimed to conduct a population pharmacokinetics (PPK) analysis of lithium and investigate the appropriateness...

Full description

Bibliographic Details
Main Authors: Zi-bin Jin, Zhuo Wu, Yi-fan Cui, Xue-peng Liu, Hong-bo Liang, Jia-yong You, Chen-yu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
lithium
bipolar disorder
population pharmacokinetics
Monte Carlo simulation
dosage regimen
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.913935/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.913935/full

Similar Items