Nuclear Deformation in Response to Mechanical Confinement is Cell Type Dependent

Mechanosensing of the mechanical microenvironment by cells regulates cell phenotype and function. The nucleus is critical in mechanosensing, as it transmits external forces from the cellular microenvironment to the nuclear envelope housing chromatin. This study aims to elucidate how mechanical confi...

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Bibliographic Details
Main Authors: Mary T. Doolin, Thea S. Ornstein, Kimberly M. Stroka
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/5/427