Thermoneutrality and severe malaria: investigating the effect of warmer environmental temperatures on the inflammatory response and disease progression

Thermoneutrality and severe malaria: investigating the effect of warmer environmental temperatures on the inflammatory response and disease progression

IntroductionMost studies using murine disease models are conducted at housing temperatures (20 – 22°C) that are sub-optimal (ST) for mice, eliciting changes in metabolism and response to disease. Experiments performed at a thermoneutral temperature (TT; 28 – 31°C) have revealed an altered immune res...

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Bibliographic Details
Main Authors: Fiorella Vialard, Isabelle Allaeys, George Dong, Minh Phuong Phan, Urvashi Singh, Marie Josée Hébert, Mélanie Dieudé, David Langlais, Eric Boilard, David P. Labbé, Martin Olivier
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
thermoneutrality
malaria
Leishmania
extracellular vesicles
Plasmodium berghei ANKA
Leishmania major
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1128466/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1128466/full

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