Circulating tumor DNA tracking through driver mutations as a liquid biopsy-based biomarker for uveal melanoma

Circulating tumor DNA tracking through driver mutations as a liquid biopsy-based biomarker for uveal melanoma

Abstract Background Uveal melanoma (UM) is the most common intraocular tumor in adults. Despite good primary tumor control, up to 50% of patients develop metastasis, which is lethal. UM often presents asymptomatically and is usually diagnosed by clinical examination and imaging, making it one of the...

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Bibliographic Details
Main Authors: Prisca Bustamante, Thupten Tsering, Jacqueline Coblentz, Christina Mastromonaco, Mohamed Abdouh, Cristina Fonseca, Rita P. Proença, Nadya Blanchard, Claude Laure Dugé, Rafaella Atherino Schmidt Andujar, Emma Youhnovska, Miguel N. Burnier, Sonia A. Callejo, Julia V. Burnier
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Circulating tumor DNA
Liquid biopsy
Uveal melanoma
Choroidal nevi
Biomarker
Mutated driver genes
Online Access:https://doi.org/10.1186/s13046-021-01984-w

Internet

https://doi.org/10.1186/s13046-021-01984-w

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