Indoxyl Sulfate-Mediated Metabolic Alteration of Transcriptome Signatures in Monocytes of Patients with End-Stage Renal Disease (ESRD)

Indoxyl Sulfate-Mediated Metabolic Alteration of Transcriptome Signatures in Monocytes of Patients with End-Stage Renal Disease (ESRD)

End-stage renal disease (ESRD) is the final stage of chronic kidney disease, which is increasingly prevalent worldwide and is associated with the progression of cardiovascular disease (CVD). Indoxyl sulfate (IS), a major uremic toxin, plays a key role in the pathology of CVD via adverse effects in e...

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Bibliographic Details
Main Authors: Hee Young Kim, Su Jeong Lee, Yuri Hwang, Ga Hye Lee, Chae Eun Yoon, Hyeon Chang Kim, Tae-Hyun Yoo, Won-Woo Lee
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Toxins
Subjects:
end-stage renal disease (ESRD)
monocytes
uremic toxins
indoxyl sulfate (IS)
aryl hydrocarbon receptor
transcriptomic analysis
Online Access:https://www.mdpi.com/2072-6651/12/10/621

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https://www.mdpi.com/2072-6651/12/10/621

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