Prenatal methadone exposure selectively alters protein expression in primary motor cortex: Implications for synaptic function

Prenatal methadone exposure selectively alters protein expression in primary motor cortex: Implications for synaptic function

As problematic opioid use has reached epidemic levels over the past 2 decades, the annual prevalence of opioid use disorder (OUD) in pregnant women has also increased 333%. Yet, how opioids affect the developing brain of offspring from mothers experiencing OUD remains understudied and not fully unde...

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Bibliographic Details
Main Authors: David L. Haggerty, Gregory G. Grecco, Jui-Yen Huang, Emma H. Doud, Amber L. Mosley, Hui-Chen Lu, Brady K. Atwood
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
methadone
prenatal opiate exposure
motor cortex
proteomics & bioinformatics
glutamatergic synapse
neurodevelopment
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1124108/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1124108/full

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