Mitophagy, metabolism, and cell fate

Mitophagy is the process by which cells eliminate damaged or superfluous mitochondria by degrading them within lysosomes. We show that during development, selective removal of mitochondria by autophagy induces a metabolic shift toward glycolysis that is essential for differentiation of several cell...

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Bibliographic Details
Main Authors: Lorena Esteban-Martínez, Elena Sierra-Filardi, Patricia Boya
Format: Article
Language:English
Published: Taylor & Francis Group 2017-09-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2017.1353854